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Chemical-Resistant Plastics: Compatibility Chart by Chemical Type

Which plastics hold up to acids, caustics, solvents, fuels and hot water? A general chemical resistance chart for PTFE, PVDF, PP, PE, PVC, CPVC, PEEK, acetal, nylon, polycarbonate and more, plus how to choose.

Reviewed October 2026 · Typical values. Always confirm with the grade datasheet.

Quick answer

For the broadest chemical resistance, PTFE is nearly universal. For tanks, piping and fabricated equipment, polypropylene, PE, PVC/CPVC and PVDF cover most acids, caustics and salts at lower cost. For high temperatures and steam, PEEK and PPS. Avoid acetal, nylon, polycarbonate and acrylic in aggressive chemical service.

Chemical resistance chart

General ratings at room temperature. E = excellent, G = good, F = fair or limited, P = poor or not recommended.

Swipe the chart sideways to see all columns →

PlasticDilute acidsStrong / oxidizing acidsBases / causticsOrganic solventsOils & fuelsHot water / steam
PTFEEEEEEE
PVDFEEFGEG
PEEKEFEEEE
PPSEFEEEE
PolypropyleneEFEFGG
HDPE / UHMWEFEFGF
PVCEGEPGP
CPVCEGEPGG
Ultem (PEI)GFFFEG
AcetalFPGEEF
NylonFPGEEF
PolycarbonateGPPPGF
AcrylicGPGPFP

General guidance by chemical family at room temperature. Ratings drop at higher temperatures and concentrations; specific chemicals can be exceptions.

Reading the chart

  • Strong and oxidizing acids (concentrated nitric, sulfuric, chromic) are the toughest test. PTFE and PVDF handle them; most others don't.
  • Bases and caustics are where PVDF, polycarbonate and Ultem are weakest, and where PP, PE, PVC and PEEK shine.
  • Organic solvents vary widely. Ketones (acetone, MEK), chlorinated and aromatic solvents attack PVC, polycarbonate and acrylic and swell PE and PP. Acetal and nylon handle most solvents well.
  • Temperature changes everything. A plastic rated "E" at room temperature may be only fair at 150°F. Check ratings at your operating temperature.

Common picks by application

Tanks, plating and chemical handling

  • Polypropylene (most acids, caustics)
  • HDPE (drums, tanks, liners)
  • PVDF (strong acids, oxidizers, high purity)

Piping, duct and fume exhaust

  • PVC (room temperature)
  • CPVC (hot chemicals to ~200°F)
  • PP and PVDF (welded systems)

Machined parts in harsh service

  • PEEK and PPS (heat plus chemicals)
  • PTFE (seals, gaskets, lined parts)
  • PVDF (pumps, valves, fittings)

Welded tanks and duct? See plastic welding and fabrication shops.

Tip from the counter: when someone asks for "something chemical resistant," ask for the exact chemical, concentration and temperature, and whether the part is under stress. Stress cracking from a cleaner is one of the most common plastic failures.

Related: PVDF vs PTFE, high-temperature plastics chart.

Common questions

Which plastic is the most chemical resistant?

PTFE (Teflon) and other fully fluorinated plastics like PFA and FEP resist almost every chemical, including strong acids, bases and solvents, at high temperatures. The practical trade-offs are cost, softness and the fact that PTFE can't be welded or easily fabricated. PVDF, PP and PEEK cover most chemical applications at lower cost or with better mechanical properties.

Is polypropylene chemically resistant?

Yes. Polypropylene resists most acids, bases and salt solutions very well and is a workhorse for tanks, plating lines and chemical handling at moderate temperatures. It's weaker against strong oxidizers (like concentrated nitric acid) and some aromatic and chlorinated solvents, which can swell it.

Is PVC plastic chemical resistant?

PVC resists most acids, bases and salts well at room temperature and is widely used for chemical piping, tanks and duct. It's attacked by many organic solvents (ketones, chlorinated and aromatic solvents) and is limited to about 140°F. CPVC extends the temperature range to about 200°F.

Is HDPE plastic chemical resistant?

Yes, HDPE and UHMW resist most acids, bases and alcohols very well, which is why HDPE is used for chemical drums and tanks. Like PP, they can swell with some hydrocarbons and solvents and are weakened by strong oxidizers, and their temperature limit is low (about 180°F).

Which plastics should I avoid around strong acids?

Acetal (Delrin) and nylon are attacked by strong acids and shouldn't be used for acid service. Polycarbonate and acrylic are also poor choices with many chemicals. For acids, look at PVDF, PP, PE, PVC/CPVC, PTFE and, for higher temperatures, PEEK (except concentrated sulfuric and nitric acid).

Always check the specific chemical

This chart is a general guide by chemical family only. Resistance depends on the exact chemical, its concentration, temperature, exposure time and stress on the part, and a plastic rated well for a family can still fail with one specific chemical. Check the manufacturer's chemical resistance data for your exact grade and chemical, review the material certifications, and test or confirm with your supplier before you specify.

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